Synthesis and Heterocyclizations of 3,4-Dihydroquinazolin-2-yl Guanidine in the Search of New Anticancer Agents

The cyclocondensations of 3,4-dihydroquinazolin-2-yl guanidine with a variety of electrophilic reagents viz. aldehydes, ketones, triethyl orthoformate, diethyl ethoxymethylenemalonate, carbon disulfide and trichloroacetonitrile were found to afford 1,3,5-triazino[2,1-b]quinazolines. However, some un...

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Bibliographic Details
Main Authors: Dolzhenko, Anton, Foo, M., Tan, B., Dolzhenko, A., Chiu, G., Chui, W.
Format: Journal Article
Published: The Japan Institute of Heterocyclic Chemistry 2009
Online Access:http://hdl.handle.net/20.500.11937/13442