Exendin-4 protects rat islets against loss of viability and function induced by brain death

Islet quality loss after isolation from brain-dead donors still hinders the implementation of human islet transplantation for treatment of type 1 diabetes. In this scenario, systemic inflammation elicited by donor brain death (BD) is among the main factors influencing islet viability and functional...

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Bibliographic Details
Main Authors: Carlessi, Rodrigo, Lemos, N., Dias, A., Oliveira, F., Brondani, L., Canani, L., Bauer, A., Leitão, C., Crispim, D.
Format: Journal Article
Published: Elsevier Ireland Ltd 2014
Online Access:http://hdl.handle.net/20.500.11937/12083