Leukotriene pathway polymorphisms are associated with altered cysteinyl leukotriene production in children with acute asthma

Cysteinyl leukotrienes (cysLTs) are pro-inflammatory mediators with increasing evidence for a role in childhood acute asthma. This study examined the influence of polymorphisms in cysLT pathway genes on urinary leukotriene E4 (uLTE4) levels and clinical status in acute asthmatic children. Children a...

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Bibliographic Details
Main Authors: Bizzintino, J., Khoo, S., Zhang, Guicheng, Martin, A., Rueter, K., Geelhoed, G., Goldblatt, J., Laing, I., Le Souëf, P., Hayden, C.
Format: Journal Article
Published: 2009
Online Access:http://hdl.handle.net/20.500.11937/10862