Comparison of single high-dose streptozotocin with partial pancreatectomy combined with low-dose streptozotocin for diabetes induction in rhesus monkeys
Monkeys with insulin-dependent diabetes are important experimental models for islet xenotransplantation. However, with regard to diabetes induction, total pancreatectomy is a difficult operation with a high complication rate, while streptozotocin (STZ) administration may cause serious toxic effects...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
SAGE Publications Inc.
2010
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| Online Access: | http://hdl.handle.net/20.500.11937/10843 |