The Guinea Pig as a Model for Sporadic Alzheimer’s Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes

The Guinea Pig as a Model for Sporadic Alzheimer’s Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes

We investigated the guinea pig, Cavia porcellus, as a model for Alzheimer’s disease (AD), both in terms of the conservation of genes involved in AD and the regulatory responses of these to a known AD risk factor - high cholesterol intake. Unlike rats and mice, guinea pigs possess an Ab peptide seque...

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Bibliographic Details
Main Authors: Sharman, Matthew, Moussavi Nik, Seyyed, Chen, Mengqi, Ong, Daniel, Wijaya, Linda, Laws, Simon, Taddei, Kevin, Newman, Morgan, Lardelli, Michael, Martins, Ralph, Verdile, Giuseppe
Format: Journal Article
Published: Public Library of Science 2013
Subjects:
AD-Related Genes
Cholesterol Intake
Alzheimer’s Disease
Online Access:http://hdl.handle.net/20.500.11937/10783

Internet

http://hdl.handle.net/20.500.11937/10783

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