C-kit Inhibition by Imatinib Mesylate Attenuates Progenitor Cell Expansion and Inhibits Liver Tumor Formation in Mice

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C-kit Inhibition by Imatinib Mesylate Attenuates Progenitor Cell Expansion and Inhibits Liver Tumor Formation in Mice

Background & Aims: Numerous studies have linked the proliferation of liver progenitor cells (LPCs) during chronic liver disease to the risk for development of hepatocellular carcinoma. Thus, selective inhibition of LPC growth during preneoplastic injury may prevent or delay the onset of liver ca...

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Bibliographic Details
Main Authors:	Knight, B., Tirnitz-Parker, Nina, Olynyk, John
Format:	Journal Article
Published:	W.B. Saunders Co. 2008
Online Access:	http://hdl.handle.net/20.500.11937/10579

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