C-kit Inhibition by Imatinib Mesylate Attenuates Progenitor Cell Expansion and Inhibits Liver Tumor Formation in Mice
Background & Aims: Numerous studies have linked the proliferation of liver progenitor cells (LPCs) during chronic liver disease to the risk for development of hepatocellular carcinoma. Thus, selective inhibition of LPC growth during preneoplastic injury may prevent or delay the onset of liver ca...
| Main Authors: | , , |
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| Format: | Journal Article |
| Published: |
W.B. Saunders Co.
2008
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| Online Access: | http://hdl.handle.net/20.500.11937/10579 |