Epigenetic regulation of the secreted frizzled-related protein family in human glioblastoma multiforme

Glioblastoma multiforme (GBM) are intracranial tumors of the central nervous system and the most lethal among solid tumors. Current therapy is palliative and is limited to surgical resection followed by radiation therapy and temozolomide treatment. Aberrant WNT pathway activation mediates not only c...

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Bibliographic Details
Main Authors: Schiefer, L., Visweswaran, Malini, Perumal, Vanathi, Arfuso, Frank, Groth, David, Newsholme, Philip, Warrier, Sudha, Dharmarajan, Arunasalam
Format: Journal Article
Published: Nature Publishing Group 2014
Online Access:http://hdl.handle.net/20.500.11937/10003