A three-dimensional collagen construct to model lipopolysaccharide-induced activation of BV2 microglia
Background: We report a novel method of culturing microglia in three dimension (3D) using collagen as a substrate. By culturing microglia within a matrix, we aim to emulate the physical state of microglia embedded within parenchyma. Methods: BV2 microglia cell suspensions were prepared with type I c...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BioMed Central
2014
|
Online Access: | http://psasir.upm.edu.my/id/eprint/36302/ http://psasir.upm.edu.my/id/eprint/36302/ http://psasir.upm.edu.my/id/eprint/36302/ http://psasir.upm.edu.my/id/eprint/36302/1/A%20three.pdf |