Transgene Silencing Following Lentiviral Gene Delivery into Hematopoietic Stem Cells
Gene therapy shows increasing promise for the treatment of hematopoietic inherited diseases such as β-thalassemia. One of the main barriers for a successful gene therapy is the short-lived duration of gene expression in vivo, a phenomenon known as transgene silencing. Unlike other viral methods, len...
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| Format: | Thesis |
| Language: | English English |
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2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/21839/ http://psasir.upm.edu.my/id/eprint/21839/1/FPSK%28p%29_2011_7IR.pdf |