Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia

Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia

This cross-sectional comparative study investigates the association between particulate matters (PM; PM10, PM2.5 and ultrafine particle (UFP) and concentration of biomarkers; Interleukin-6 (IL-6) and Tumor Necrosis Factor-Alpha (TNF-α) using 62 bus drivers as exposed group and 62 administrative staf...

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Main Authors: M., Kavitha, Jalaludin, Juliana, Md. Akim, Abdah
Format: Article
Language:English
Published: School of Health Sciences, Universiti Sains Malaysia 2011
Online Access:http://psasir.upm.edu.my/id/eprint/17307/
http://psasir.upm.edu.my/id/eprint/17307/
http://psasir.upm.edu.my/id/eprint/17307/1/Relationship%20between%20exposure%20to%20particulate%20matter%20and%20biomarkers%20among%20bus%20drivers%20in%20Klang%20Valley%2C%20Malaysia.pdf
id upm-17307
recordtype eprints
spelling upm-173072016-04-08T07:58:00Z http://psasir.upm.edu.my/id/eprint/17307/ Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia M., Kavitha Jalaludin, Juliana Md. Akim, Abdah This cross-sectional comparative study investigates the association between particulate matters (PM; PM10, PM2.5 and ultrafine particle (UFP) and concentration of biomarkers; Interleukin-6 (IL-6) and Tumor Necrosis Factor-Alpha (TNF-α) using 62 bus drivers as exposed group and 62 administrative staff as comparative group in Klang Valley, Malaysia. T-test results showed that the mean exposure level of PM10 (t = 8.14, p<0.01), PM2.5 (t = 9.95, p<0.01) and UFP (t = 19.61, p<0.01) were significantly higher among the bus drivers compared to comparative group. Mann-Whitney U test of IL-6 (z = -2.43, p<0.05) and TNF-α (z = -5.88, p<0.01) were also found to be significantly higher in the bus drivers. Positive correlations were found between the exposure level of PM and concentration of biomarkers. In conclusion, the bus drivers showed higher concentration of IL-6 and TNF-α and were at a higher risk of getting respiratory illnesses compared to comparative group. Thus, more attention should be e given on the control of high level of exposure to PM in order to minimize the adverse health effects among the groups at risk. School of Health Sciences, Universiti Sains Malaysia 2011-05-31 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/17307/1/Relationship%20between%20exposure%20to%20particulate%20matter%20and%20biomarkers%20among%20bus%20drivers%20in%20Klang%20Valley%2C%20Malaysia.pdf M., Kavitha and Jalaludin, Juliana and Md. Akim, Abdah (2011) Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia. Health and the Environment Journal, 2 (2). pp. 1-7. ISSN 180-1126 http://www.hej.kk.usm.my/volume2no2.php
repository_type Digital Repository
institution_category Local University
institution Universiti Putra Malaysia
building UPM Institutional Repository
collection Online Access
language English
description This cross-sectional comparative study investigates the association between particulate matters (PM; PM10, PM2.5 and ultrafine particle (UFP) and concentration of biomarkers; Interleukin-6 (IL-6) and Tumor Necrosis Factor-Alpha (TNF-α) using 62 bus drivers as exposed group and 62 administrative staff as comparative group in Klang Valley, Malaysia. T-test results showed that the mean exposure level of PM10 (t = 8.14, p<0.01), PM2.5 (t = 9.95, p<0.01) and UFP (t = 19.61, p<0.01) were significantly higher among the bus drivers compared to comparative group. Mann-Whitney U test of IL-6 (z = -2.43, p<0.05) and TNF-α (z = -5.88, p<0.01) were also found to be significantly higher in the bus drivers. Positive correlations were found between the exposure level of PM and concentration of biomarkers. In conclusion, the bus drivers showed higher concentration of IL-6 and TNF-α and were at a higher risk of getting respiratory illnesses compared to comparative group. Thus, more attention should be e given on the control of high level of exposure to PM in order to minimize the adverse health effects among the groups at risk.
format Article
author M., Kavitha
Jalaludin, Juliana
Md. Akim, Abdah
spellingShingle M., Kavitha
Jalaludin, Juliana
Md. Akim, Abdah
Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia
author_facet M., Kavitha
Jalaludin, Juliana
Md. Akim, Abdah
author_sort M., Kavitha
title Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia
title_short Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia
title_full Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia
title_fullStr Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia
title_full_unstemmed Relationship between exposure to particulate matter and biomarkers among bus drivers in Klang Valley, Malaysia
title_sort relationship between exposure to particulate matter and biomarkers among bus drivers in klang valley, malaysia
publisher School of Health Sciences, Universiti Sains Malaysia
publishDate 2011
url http://psasir.upm.edu.my/id/eprint/17307/
http://psasir.upm.edu.my/id/eprint/17307/
http://psasir.upm.edu.my/id/eprint/17307/1/Relationship%20between%20exposure%20to%20particulate%20matter%20and%20biomarkers%20among%20bus%20drivers%20in%20Klang%20Valley%2C%20Malaysia.pdf
first_indexed 2018-09-07T13:52:56Z
last_indexed 2018-09-07T13:52:56Z
_version_ 1610957063559577600

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