Serovar diversity of Leptospira sp. infecting wild rodents in Sarawak, Malaysia

Leptopsirosis is a zoonotic disease with global distribution and rodents, in particular rats, have been identified as the main reservoir host. A study was conducted to determine the prevalence of antibodies against Leptospira sp. in wild rodents caught in selected areas of Sibu, Sarikei and Kapit...

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Main Authors:	Lela, Suut, Azim Mazlan, M.N, Mohd Taha, Arif, Joseph Tau, Anak Katip, Nor Aliza,, A.R, Haironi,, Y
Format:	Article
Language:	English
Published:	Malaysian Society of Parasitology and Tropical Medicine 2018
Subjects:	QL Zoology R Medicine (General) RB Pathology
Online Access:	http://ir.unimas.my/19849/ http://ir.unimas.my/19849/ http://ir.unimas.my/19849/1/Serovar%20diversity%20of%20Leptospira%20sp.%20infecting%20wild%20rodents%20%28abstrak%29.pdf

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spelling	unimas-198492018-03-19T03:15:58Z http://ir.unimas.my/19849/ Serovar diversity of Leptospira sp. infecting wild rodents in Sarawak, Malaysia Lela, Suut Azim Mazlan, M.N Mohd Taha, Arif Joseph Tau, Anak Katip Nor Aliza,, A.R Haironi,, Y QL Zoology R Medicine (General) RB Pathology Leptopsirosis is a zoonotic disease with global distribution and rodents, in particular rats, have been identified as the main reservoir host. A study was conducted to determine the prevalence of antibodies against Leptospira sp. in wild rodents caught in selected areas of Sibu, Sarikei and Kapit in Sarawak during the period of July 2011 to May 2014. In total, 241 sera samples were collected from rodents caught from these three administrative divisions in Sarawak. Ninety-eight rodents (40.7%) were positive with antibody titre >1:50 by microscopic agglutination test (MAT) against 13 out of 20 common local leptospiral serovars tested. Sera of rodents caught in Sibu, Kapit and Sarikei divisions were positive at 43.9%, 37.5% and 36.4%, respectively. The top five serovars detected were: Autumnalis (25.5%), Tarassovi (23.5%), Bataviae (15.3%), Hebdomadis (8.2%) and Celledoni (7.2%). The main species of rodent positive for antibodies against Leptopsira sp. were Sundamys muelleri (50.0%), Rattus rattus (37.5%), Callociurus notatus (35.6%) and Rattus exulans (32.6%). This study indicates that leptospiral antibodies are prevalent amongst wild rodents in central Sarawak, which could be translated as high leptospiral carriage. The close interaction that exists between the local community and the environment could potentially propagate the transmission of Leptospira sp. to human in these areas. This study also provided essential information about local circulating Leptospira serovars, which could be useful for eventual prevention measures in disease transmission Malaysian Society of Parasitology and Tropical Medicine 2018 Article PeerReviewed text en http://ir.unimas.my/19849/1/Serovar%20diversity%20of%20Leptospira%20sp.%20infecting%20wild%20rodents%20%28abstrak%29.pdf Lela, Suut and Azim Mazlan, M.N and Mohd Taha, Arif and Joseph Tau, Anak Katip and Nor Aliza,, A.R and Haironi,, Y (2018) Serovar diversity of Leptospira sp. infecting wild rodents in Sarawak, Malaysia. Tropical Biomedicine, 35 (1). pp. 252-258. ISSN 01275720 http://msptm.org/vol-35-no-1/
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Sarawak
building	UNIMAS Institutional Repository
collection	Online Access
language	English
topic	QL Zoology R Medicine (General) RB Pathology
spellingShingle	QL Zoology R Medicine (General) RB Pathology Lela, Suut Azim Mazlan, M.N Mohd Taha, Arif Joseph Tau, Anak Katip Nor Aliza,, A.R Haironi,, Y Serovar diversity of Leptospira sp. infecting wild rodents in Sarawak, Malaysia
description	Leptopsirosis is a zoonotic disease with global distribution and rodents, in particular rats, have been identified as the main reservoir host. A study was conducted to determine the prevalence of antibodies against Leptospira sp. in wild rodents caught in selected areas of Sibu, Sarikei and Kapit in Sarawak during the period of July 2011 to May 2014. In total, 241 sera samples were collected from rodents caught from these three administrative divisions in Sarawak. Ninety-eight rodents (40.7%) were positive with antibody titre >1:50 by microscopic agglutination test (MAT) against 13 out of 20 common local leptospiral serovars tested. Sera of rodents caught in Sibu, Kapit and Sarikei divisions were positive at 43.9%, 37.5% and 36.4%, respectively. The top five serovars detected were: Autumnalis (25.5%), Tarassovi (23.5%), Bataviae (15.3%), Hebdomadis (8.2%) and Celledoni (7.2%). The main species of rodent positive for antibodies against Leptopsira sp. were Sundamys muelleri (50.0%), Rattus rattus (37.5%), Callociurus notatus (35.6%) and Rattus exulans (32.6%). This study indicates that leptospiral antibodies are prevalent amongst wild rodents in central Sarawak, which could be translated as high leptospiral carriage. The close interaction that exists between the local community and the environment could potentially propagate the transmission of Leptospira sp. to human in these areas. This study also provided essential information about local circulating Leptospira serovars, which could be useful for eventual prevention measures in disease transmission
format	Article
author	Lela, Suut Azim Mazlan, M.N Mohd Taha, Arif Joseph Tau, Anak Katip Nor Aliza,, A.R Haironi,, Y
author_facet	Lela, Suut Azim Mazlan, M.N Mohd Taha, Arif Joseph Tau, Anak Katip Nor Aliza,, A.R Haironi,, Y
author_sort	Lela, Suut
title	Serovar diversity of Leptospira sp. infecting wild rodents in Sarawak, Malaysia
title_short	Serovar diversity of Leptospira sp. infecting wild rodents in Sarawak, Malaysia
title_full	Serovar diversity of Leptospira sp. infecting wild rodents in Sarawak, Malaysia
title_fullStr	Serovar diversity of Leptospira sp. infecting wild rodents in Sarawak, Malaysia
title_full_unstemmed	Serovar diversity of Leptospira sp. infecting wild rodents in Sarawak, Malaysia
title_sort	serovar diversity of leptospira sp. infecting wild rodents in sarawak, malaysia
publisher	Malaysian Society of Parasitology and Tropical Medicine
publishDate	2018
url	http://ir.unimas.my/19849/ http://ir.unimas.my/19849/ http://ir.unimas.my/19849/1/Serovar%20diversity%20of%20Leptospira%20sp.%20infecting%20wild%20rodents%20%28abstrak%29.pdf
first_indexed	2018-09-06T16:51:54Z
last_indexed	2018-09-06T16:51:54Z
_version_	1610877726208557056

Serovar diversity of Leptospira sp. infecting wild rodents in Sarawak, Malaysia

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