Synthesis, characterization and antibacterial activity of bis thiourea derivatives

A series of bisthiourea derivatives were succesfully synthesized by reaction of benzene-1, 4 dicarbonyl isothiocyanate intermediates and isophthaloyl dichloride, with a series of aromatic amine at ortho, meta and para position. The structure of synthesised compound characterized by infra-red spect...

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Main Author:	Jayakumar, Ponniasalan
Format:	Project Report
Language:	English English
Published:	Universiti Malaysia Sarawak, (UNIMAS) 2015
Subjects:	RV Botanic, Thomsonian, and eclectic medicine
Online Access:	http://ir.unimas.my/11053/ http://ir.unimas.my/11053/1/Synthesis%2C%20Characterization%20and%20Antibacterial%20Acitivty%20of%20Bis%20Thiourea%20Derivatives%20%2824%20pages%29.pdf http://ir.unimas.my/11053/2/Synthesis%2C%20Characterization%20and%20Antibacterial%20Acitivty%20of%20Bis%20Thiourea%20Derivatives%20%28fulltext%29.pdf

id	unimas-11053
recordtype	eprints
spelling	unimas-110532016-03-21T08:00:50Z http://ir.unimas.my/11053/ Synthesis, characterization and antibacterial activity of bis thiourea derivatives Jayakumar, Ponniasalan RV Botanic, Thomsonian, and eclectic medicine A series of bisthiourea derivatives were succesfully synthesized by reaction of benzene-1, 4 dicarbonyl isothiocyanate intermediates and isophthaloyl dichloride, with a series of aromatic amine at ortho, meta and para position. The structure of synthesised compound characterized by infra-red spectroscopy (FTIR), 1H Nuclear magnetic resonances, and 13C Nuclear magnetic resonances. The synthesised compounds were screened for their antibacterial properties using Gram-negative bacteria Escherichia coli (E.coli) by using disc diffusion method. All of synthesized series showed negative results towards antibacterial activity. Universiti Malaysia Sarawak, (UNIMAS) 2015 Project Report NonPeerReviewed text en http://ir.unimas.my/11053/1/Synthesis%2C%20Characterization%20and%20Antibacterial%20Acitivty%20of%20Bis%20Thiourea%20Derivatives%20%2824%20pages%29.pdf text en http://ir.unimas.my/11053/2/Synthesis%2C%20Characterization%20and%20Antibacterial%20Acitivty%20of%20Bis%20Thiourea%20Derivatives%20%28fulltext%29.pdf Jayakumar, Ponniasalan (2015) Synthesis, characterization and antibacterial activity of bis thiourea derivatives. [Project Report] (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Sarawak
building	UNIMAS Institutional Repository
collection	Online Access
language	English English
topic	RV Botanic, Thomsonian, and eclectic medicine
spellingShingle	RV Botanic, Thomsonian, and eclectic medicine Jayakumar, Ponniasalan Synthesis, characterization and antibacterial activity of bis thiourea derivatives
description	A series of bisthiourea derivatives were succesfully synthesized by reaction of benzene-1, 4 dicarbonyl isothiocyanate intermediates and isophthaloyl dichloride, with a series of aromatic amine at ortho, meta and para position. The structure of synthesised compound characterized by infra-red spectroscopy (FTIR), 1H Nuclear magnetic resonances, and 13C Nuclear magnetic resonances. The synthesised compounds were screened for their antibacterial properties using Gram-negative bacteria Escherichia coli (E.coli) by using disc diffusion method. All of synthesized series showed negative results towards antibacterial activity.
format	Project Report
author	Jayakumar, Ponniasalan
author_facet	Jayakumar, Ponniasalan
author_sort	Jayakumar, Ponniasalan
title	Synthesis, characterization and antibacterial activity of bis thiourea derivatives
title_short	Synthesis, characterization and antibacterial activity of bis thiourea derivatives
title_full	Synthesis, characterization and antibacterial activity of bis thiourea derivatives
title_fullStr	Synthesis, characterization and antibacterial activity of bis thiourea derivatives
title_full_unstemmed	Synthesis, characterization and antibacterial activity of bis thiourea derivatives
title_sort	synthesis, characterization and antibacterial activity of bis thiourea derivatives
publisher	Universiti Malaysia Sarawak, (UNIMAS)
publishDate	2015
url	http://ir.unimas.my/11053/ http://ir.unimas.my/11053/1/Synthesis%2C%20Characterization%20and%20Antibacterial%20Acitivty%20of%20Bis%20Thiourea%20Derivatives%20%2824%20pages%29.pdf http://ir.unimas.my/11053/2/Synthesis%2C%20Characterization%20and%20Antibacterial%20Acitivty%20of%20Bis%20Thiourea%20Derivatives%20%28fulltext%29.pdf
first_indexed	2018-09-06T15:51:18Z
last_indexed	2018-09-06T15:51:18Z
_version_	1610873913705758720

Synthesis, characterization and antibacterial activity of bis thiourea derivatives

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