Challenges associated with the synthesis of unusual O-Carboxamido Stilbenes by the Heck Protocol: intriguing substituent effects, their toxicological and chemopreventive implications

Challenges associated with the synthesis of unusual O-Carboxamido Stilbenes by the Heck Protocol: intriguing substituent effects, their toxicological and chemopreventive implications

The syntheses of fourteen unusual o-carboxamido stilbenes by the Heck protocol revealed surprising complexity related to intriguing substituent effects with mechanistic implications. The unexpected cytotoxic and chemopreventive properties also seem to be substituent dependent. For example, although...

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Bibliographic Details
Main Authors: Ariffin, A., Thomas, N.F., Kee, C.H., Awang, K., Takeya, K., Morita, H., Hussain, S.I., Chan, K.M., Weber, J.F.F., Wood, P.J., Threadgill, M.D., Lim, C.G., Ng, S.
Format: Article
Published: 2010
Subjects:
QD Chemistry
Online Access:http://pubs.rsc.org/en/content/articlepdf/2010/ob/c0ob00296h
http://pubs.rsc.org/en/content/articlepdf/2010/ob/c0ob00296h
http://eprints.um.edu.my/8086/1/Kee%2D2010%2DChallenges_associate.pdf

Internet

http://pubs.rsc.org/en/content/articlepdf/2010/ob/c0ob00296h
http://pubs.rsc.org/en/content/articlepdf/2010/ob/c0ob00296h
http://eprints.um.edu.my/8086/1/Kee%2D2010%2DChallenges_associate.pdf

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