Ultraviolet-visible study on acid-base equilibria of aporphine alkaloids with antiplasmodial and antioxidant activities from Alseodaphne corneri and Dehaasia longipedicellata

The UV-vis spectra of isocorydine 1, norisocorydine 2 and boldine 3 were studied in 2% v/v acetonitrile, at constant ionic strength (0.1 M NaCl, 35 degree Celsius). The pKa values of isocorydine 1 and norisocorydine 2 were 11.75 and 12.07, respectively. Boldine 3 gave a pKa value of 9.16 and 10.44....

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Bibliographic Details
Main Authors: Zahari, A., Ablat, A., Omer, N., Nafiah, M.A., Sivasothy, Y., Mohamad, J., Khan, M.N., Awang, K.
Format: Article
Published: Nature Publishing Group 2016
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Online Access:http://dx.doi.org/10.1038/srep21517
http://dx.doi.org/10.1038/srep21517