Pictet-Spengler reaction-based biosynthetic machinery in fungi

The Pictet-Spengler (PS) reaction constructs plant alkaloids such as morphine and camptothecin, but it has not yet been noticed in the fungal kingdom. Here, a silent fungal Pictet-Spenglerase (FPS) gene of Chaetomium globosum 1C51 residing in Epinephelus drummondhayi guts is described and ascertaine...

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Bibliographic Details
Main Authors: Yan, W., Ge, H.M., Wang, G., Jiang, N., Mei, Y.N., Jiang, R., Li, S.J., Chen, C.J., Jiao, R.H., Xu, Q., Ng, Seik Weng, Tan, R.X.
Format: Article
Published: National Academy of Sciences 2014
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Online Access:http://eprints.um.edu.my/15385/