Alternative animal model for Pasteurella multocida and Haemorrhagic septicaemia
A suitable animal model is essential in understanding a condition caused by microorganisms. In this study in order to study the changes in haemorrahgic septicaemia caused by Pasteurella multocida serotype B, Sprague-Dawley (SK/WDY) rats were immuo-suppressed with dexamethasone and challenged with P....
| Main Authors: | , , , , |
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| Format: | Article |
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Biomedical Research Press
2013
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| Online Access: | http://www.alliedacademies.org/articles/alternative-animal-model-for-pasteurella-multocida-and-haemorrhagicsepticaemia.pdf http://www.alliedacademies.org/articles/alternative-animal-model-for-pasteurella-multocida-and-haemorrhagicsepticaemia.pdf |
| Summary: | A suitable animal model is essential in understanding a condition caused by microorganisms. In this study in order to study the changes in haemorrahgic septicaemia caused by Pasteurella multocida serotype B, Sprague-Dawley (SK/WDY) rats were immuo-suppressed with dexamethasone and challenged with P.multocida serotype B:2. The animals were monitored/inspected twice daily. Any changes in behaviour, movement, eating and development of any signs and symptoms were recorded. Immune-suppressed rats showed signs of haemorrahge and lesion in the lungs. |
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