Antioxidant and antiglycemic potential of Peltophorum pterocarpum plant parts

The leaf and bark extracts of Peltophorum pterocarpum were evaluated for their DPPH, ARTS, and galvinoxyl radicals scavenging activity, phenolic content, alpha-glucosidase, alpha-amylase and aldose reductase inhibition, and advanced glycation end-products formation inhibition activities. These extra...

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Bibliographic Details
Main Authors: Manaharan, T., Teng, L.L., Appleton, D., Ming, C.H., Masilamani, T., Palanisamy, U.D.
Format: Article
Published: Elsevier 2011
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Online Access:http://eprints.um.edu.my/14547/
Description
Summary:The leaf and bark extracts of Peltophorum pterocarpum were evaluated for their DPPH, ARTS, and galvinoxyl radicals scavenging activity, phenolic content, alpha-glucosidase, alpha-amylase and aldose reductase inhibition, and advanced glycation end-products formation inhibition activities. These extracts showed a far more significant antiglycemic activity compared to the commercial carbohydrate inhibitor, acarbose. The active compound in P. pterocarpum leaf extracts was identified to be quercetin-3-O-beta-D-galactopyranoside. Our findings provide a strong rationale for further in vivo studies and to establish P. pterocarpum's capability as an antiglycemic agent. (C) 2011 Elsevier Ltd. All rights reserved.