Establishing and managing a periodontal biobank for research: the sharing of experience

Periodontal bio-repositories, which allow banking of clinically validated human data and biological samples, provide an opportunity to derive biomarkers for periodontal diagnosis, prognosis and therapeutic activities which are expected to improve patient management. This article presents the establi...

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Main Authors:	Vaithilingam, R.D., Safii, S.H., Baharuddin, N.A., Karen-Ng, L.P., Saub, R., Ariffin, F., Ramli, H., Shariffudin, A., Hidayat, M.F.H., Raman, R., Chan, Y.K., Rani, N.A., Rahim, R.A., Shahrudidin, N., Cheong, S.C., Bartold, P.M., Zain, R.B.
Format:	Article
Published:	Blackwell Publishing 2015
Subjects:	RK Dentistry
Online Access:	http://www.ncbi.nlm.nih.gov/pubmed/24930489 http://www.ncbi.nlm.nih.gov/pubmed/24930489 http://eprints.um.edu.my/12602/1/Establishing_and_managing_a_periodontal_biobank_for_research_the_sharing_of_experience.pdf

id	um-12602
recordtype	eprints
spelling	um-126022015-02-09T04:46:50Z Establishing and managing a periodontal biobank for research: the sharing of experience Vaithilingam, R.D. Safii, S.H. Baharuddin, N.A. Karen-Ng, L.P. Saub, R. Ariffin, F. Ramli, H. Shariffudin, A. Hidayat, M.F.H. Raman, R. Chan, Y.K. Rani, N.A. Rahim, R.A. Shahrudidin, N. Cheong, S.C. Bartold, P.M. Zain, R.B. RK Dentistry Periodontal bio-repositories, which allow banking of clinically validated human data and biological samples, provide an opportunity to derive biomarkers for periodontal diagnosis, prognosis and therapeutic activities which are expected to improve patient management. This article presents the establishing of the Malaysian Periodontal Database and Biobank System (MPDBS) which was initiated in 2011 with the aim to facilitate periodontal research. Partnerships were established with collaborating centres. Policies on specimen access, authorship and acknowledgement policies were agreed upon by all participating centres before the initiation of the periodontal biobank. Ethical approval for the collection of samples and data were obtained from institutional ethics review boards. A broad-based approach for informed consent was used, which covered areas related to quality of life impacts, genetics and molecular aspects of periodontal disease. Sample collection and processing was performed using a standardized protocol. Biobanking resources such as equipment and freezers were shared with the Malaysian Oral Cancer Database and Tissue Bank System (MOCDTBS). In the development of the MPDBS, challenges that were previously faced by the MOCDTBS were considered. Future challenges in terms of ethical and legal issues will be faced when international collaborations necessitate the transportation of specimens across borders. Blackwell Publishing 2015 Article PeerReviewed application/pdf http://eprints.um.edu.my/12602/1/Establishing_and_managing_a_periodontal_biobank_for_research_the_sharing_of_experience.pdf http://www.ncbi.nlm.nih.gov/pubmed/24930489 Vaithilingam, R.D.; Safii, S.H.; Baharuddin, N.A.; Karen-Ng, L.P.; Saub, R.; Ariffin, F.; Ramli, H.; Shariffudin, A.; Hidayat, M.F.H.; Raman, R.; Chan, Y.K.; Rani, N.A.; Rahim, R.A.; Shahrudidin, N.; Cheong, S.C.; Bartold, P.M.; Zain, R.B. (2015) Establishing and managing a periodontal biobank for research: the sharing of experience. Oral Diseases <http://eprints.um.edu.my/view/publication/Oral_Diseases.html>. http://eprints.um.edu.my/12602/
repository_type	Digital Repository
institution_category	Local University
institution	University Malaya
building	UM Research Repository
collection	Online Access
topic	RK Dentistry
spellingShingle	RK Dentistry Vaithilingam, R.D. Safii, S.H. Baharuddin, N.A. Karen-Ng, L.P. Saub, R. Ariffin, F. Ramli, H. Shariffudin, A. Hidayat, M.F.H. Raman, R. Chan, Y.K. Rani, N.A. Rahim, R.A. Shahrudidin, N. Cheong, S.C. Bartold, P.M. Zain, R.B. Establishing and managing a periodontal biobank for research: the sharing of experience
description	Periodontal bio-repositories, which allow banking of clinically validated human data and biological samples, provide an opportunity to derive biomarkers for periodontal diagnosis, prognosis and therapeutic activities which are expected to improve patient management. This article presents the establishing of the Malaysian Periodontal Database and Biobank System (MPDBS) which was initiated in 2011 with the aim to facilitate periodontal research. Partnerships were established with collaborating centres. Policies on specimen access, authorship and acknowledgement policies were agreed upon by all participating centres before the initiation of the periodontal biobank. Ethical approval for the collection of samples and data were obtained from institutional ethics review boards. A broad-based approach for informed consent was used, which covered areas related to quality of life impacts, genetics and molecular aspects of periodontal disease. Sample collection and processing was performed using a standardized protocol. Biobanking resources such as equipment and freezers were shared with the Malaysian Oral Cancer Database and Tissue Bank System (MOCDTBS). In the development of the MPDBS, challenges that were previously faced by the MOCDTBS were considered. Future challenges in terms of ethical and legal issues will be faced when international collaborations necessitate the transportation of specimens across borders.
format	Article
author	Vaithilingam, R.D. Safii, S.H. Baharuddin, N.A. Karen-Ng, L.P. Saub, R. Ariffin, F. Ramli, H. Shariffudin, A. Hidayat, M.F.H. Raman, R. Chan, Y.K. Rani, N.A. Rahim, R.A. Shahrudidin, N. Cheong, S.C. Bartold, P.M. Zain, R.B.
author_facet	Vaithilingam, R.D. Safii, S.H. Baharuddin, N.A. Karen-Ng, L.P. Saub, R. Ariffin, F. Ramli, H. Shariffudin, A. Hidayat, M.F.H. Raman, R. Chan, Y.K. Rani, N.A. Rahim, R.A. Shahrudidin, N. Cheong, S.C. Bartold, P.M. Zain, R.B.
author_sort	Vaithilingam, R.D.
title	Establishing and managing a periodontal biobank for research: the sharing of experience
title_short	Establishing and managing a periodontal biobank for research: the sharing of experience
title_full	Establishing and managing a periodontal biobank for research: the sharing of experience
title_fullStr	Establishing and managing a periodontal biobank for research: the sharing of experience
title_full_unstemmed	Establishing and managing a periodontal biobank for research: the sharing of experience
title_sort	establishing and managing a periodontal biobank for research: the sharing of experience
publisher	Blackwell Publishing
publishDate	2015
url	http://www.ncbi.nlm.nih.gov/pubmed/24930489 http://www.ncbi.nlm.nih.gov/pubmed/24930489 http://eprints.um.edu.my/12602/1/Establishing_and_managing_a_periodontal_biobank_for_research_the_sharing_of_experience.pdf
first_indexed	2018-09-06T06:07:36Z
last_indexed	2018-09-06T06:07:36Z
_version_	1610837190568312832

Establishing and managing a periodontal biobank for research: the sharing of experience

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