Hypothalamic mediation of reduced GH secretion in diabetic rats: evidence for reduced cholinergic inhibition of somatostatin release

The Goto-Kakizaki (GK) rat is a new model of diabetes mellitus and in this study we have characterized the diabetic and growth hormone (GH) secretory status of male GK rats at 6 and 16 weeks of age. We have also investigated the role of endogenous somatostatin (SS) and cholinergic manipulation on th...

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Bibliographic Details
Main Authors: Ismail, I.S., Lewis, M., Peters, J.R., Scanlon, M.F.
Format: Article
Published: Blackwell Publishing 1995
Subjects:
Online Access:http://eprints.um.edu.my/10398/
http://eprints.um.edu.my/10398/1/Hypothalamic.pdf