Autoantibodies directed to novel components of the PM/Scl complex, the human exosome

The autoantigenic polymyositis/scleroderma (PM/Scl) complex was recently shown to be the human homologue of the yeast exosome, which is an RNA-processing complex. Our aim was to assess whether, in addition to targeting the known autoantigens PM/Scl-100 and PM/Scl-75, autoantibodies also target recen...

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Bibliographic Details
Main Authors: Brouwer, Rick, Vree Egberts, Wilma TM, Hengstman, Gerald JD, Raijmakers, Reinout, van Engelen, Baziel GM, Peter Seelig, Hans, Renz, Manfred, Mierau, Rudolf, Genth, Ekkehard, Pruijn, Ger JM, van Venrooij, Walther J
Format: Online
Language:English
Published: BioMed Central 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC83843/