Debate: The slippery slope of surrogate outcomes
Surrogate outcomes are frequently used in cardiovascular disease research. A concern is that changes in surrogate markers may not reflect changes in disease outcomes. Two recent clinical trials (Heart and Estrogen/Progestin Replacement Study [HERS], and the Antihypertensive and Lipid-Lowering Treatm...
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| Format: | Online |
| Language: | English |
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BioMed Central
2000
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59603/ |