Retrotransposition-Competent Human LINE-1 Induces Apoptosis in Cancer Cells With Intact p53

Retrotransposition of human LINE-1 (L1) element, a major representative non-LTR retrotransposon in the human genome, is known to be a source of insertional mutagenesis. However, nothing is known about effects of L1 retrotransposition on cell growth and differentiation. To investigate the potential f...

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Bibliographic Details
Main Authors: Haoudi, Abdelali, Semmes, O. John, Mason, James M., Cannon, Ronald E.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555774/