On the emergence of multifocal cancers

Several tumors can exist as multiple lesions within a tissue. The lesions may either arise independently, or they may be monoclonal. The importance of multiple lesions for tumor staging, progression, and treatment is subject to debate. Here we use mathematical models to analyze the emergence of mult...

Full description

Bibliographic Details
Main Authors: Wodarz, Dominik, Iwasa, Yoh, Komarova, Natalia L
Format: Online
Language:English
Published: BioMed Central 2004
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC526757/