Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma
Pediatric brain tumors may originate from cells endowed with neural stem/precursor cell properties, growing in vitro as neurospheres. We have found that these cells can also be present in adult brain tumors and form highly infiltrating gliomas in the brain of immunodeficient mice. Neurospheres were...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2004
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC524518/ |