Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans

BACKGROUND. Cardiovascular disease occurs at lower incidence in premenopausal females compared with age-matched males. This variation may be linked to sex differences in inflammation. We prospectively investigated whether inflammation and components of the inflammatory response are altered in female...

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Bibliographic Details
Main Authors: Rathod, Krishnaraj S., Kapil, Vikas, Velmurugan, Shanti, Khambata, Rayomand S., Siddique, Umme, Khan, Saima, Van Eijl, Sven, Gee, Lorna C., Bansal, Jascharanpreet, Pitrola, Kavi, Shaw, Christopher, D’Acquisto, Fulvio, Colas, Romain A., Marelli-Berg, Federica, Dalli, Jesmond, Ahluwalia, Amrita
Format: Online
Language:English
Published: American Society for Clinical Investigation 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199722/
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Summary:BACKGROUND. Cardiovascular disease occurs at lower incidence in premenopausal females compared with age-matched males. This variation may be linked to sex differences in inflammation. We prospectively investigated whether inflammation and components of the inflammatory response are altered in females compared with males.