A dual role for Caspase8 and NF-κB interactions in regulating apoptosis and necroptosis of ovarian cancer, with correlation to patient survival

A dual role for Caspase8 and NF-κB interactions in regulating apoptosis and necroptosis of ovarian cancer, with correlation to patient survival

Ovarian cancer is a deadly disease characterized by primary and acquired resistance to chemotherapy. We previously associated NF-κB signaling with poor survival in ovarian cancer, and functionally demonstrated this pathway as mediating proliferation, invasion and metastasis. We aimed to identify coo...

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Bibliographic Details
Main Authors: Hernandez, L, Kim, M K, Noonan, A M, Sagher, E, Kohlhammer, H, Wright, G, Lyle, L T, Steeg, P S, Anver, M, Bowtell, D D, Annunziata, C M
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198842/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198842/

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