Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis
Mutation of the PARK2 gene can promote both Parkinson's Disease and cancer, yet the underlying mechanisms of how PARK2 controls cellular physiology is incompletely understood. Here, we show that the PARK2 tumor suppressor controls the apoptotic regulator BCL-XL and modulates programmed cell dea...
| Main Authors: | , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Neoplasia Press
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198112/ |