Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine

Undesired immune responses have drastically hampered outcomes after allogeneic organ transplantation and cell therapy, and also lead to inflammatory diseases and autoimmunity. Umbilical cord mesenchymal stem cells (UCMSCs) have powerful regenerative and immunomodulatory potential, and their secreted...

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Bibliographic Details
Main Authors: Monguió-Tortajada, Marta, Roura, Santiago, Gálvez-Montón, Carolina, Pujal, Josep Maria, Aran, Gemma, Sanjurjo, Lucía, Franquesa, Marcel·la, Sarrias, Maria-Rosa, Bayes-Genis, Antoni, Borràs, Francesc E.
Format: Online
Language:English
Published: Ivyspring International Publisher 2017
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5197063/