Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction

Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction

Mutations affecting the apoptosis-inducing function of the Fas/CD95 TNF-family receptor result in autoimmune and lymphoproliferative disease. However, Fas can also costimulate T-cell activation and promote tumour cell growth and metastasis. Palmitoylation at a membrane proximal cysteine residue enab...

Full description

Bibliographic Details
Main Authors: Cruz, Anthony C., Ramaswamy, Madhu, Ouyang, Claudia, Klebanoff, Christopher A., Sengupta, Prabuddha, Yamamoto, Tori N., Meylan, Françoise, Thomas, Stacy K., Richoz, Nathan, Eil, Robert, Price, Susan, Casellas, Rafael, Rao, V. Koneti, Lippincott-Schwartz, Jennifer, Restifo, Nicholas P., Siegel, Richard M.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196435/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196435/

Similar Items