Dyshomeostasis, obesity, addiction and chronic stress
When eating control is overridden by hedonic reward, a condition of obesity dyshomeostasis occurs. Appetitive hedonic reward is a natural response to an obesogenic environment containing endemic stress and easily accessible and palatable high-energy foods and beverages. Obesity dyshomeostasis is med...
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| Format: | Online |
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SAGE Publications
2016
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193275/ |
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pubmed-51932752017-01-09 Dyshomeostasis, obesity, addiction and chronic stress Marks, David F Theoretical Contribution/Commentary When eating control is overridden by hedonic reward, a condition of obesity dyshomeostasis occurs. Appetitive hedonic reward is a natural response to an obesogenic environment containing endemic stress and easily accessible and palatable high-energy foods and beverages. Obesity dyshomeostasis is mediated by the prefrontal cortex, amygdala and hypothalamic–pituitary–adrenal axis. The ghrelin axis provides the perfect signalling system for feeding dyshomeostasis, affect control and hedonic reward. Dyshomeostasis plays a central role in obesity causation, the addictions and chronic conditions and in persons with diverse bodies. Prevention and treatment efforts that target sources of dyshomeostasis provide ways of reducing adiposity, ameliorating the health impacts of addiction and raising the quality of life in people suffering from chronic stress. SAGE Publications 2016-03-28 /pmc/articles/PMC5193275/ /pubmed/28070396 http://dx.doi.org/10.1177/2055102916636907 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage). |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Marks, David F |
| spellingShingle |
Marks, David F Dyshomeostasis, obesity, addiction and chronic stress |
| author_facet |
Marks, David F |
| author_sort |
Marks, David F |
| title |
Dyshomeostasis, obesity, addiction and chronic stress |
| title_short |
Dyshomeostasis, obesity, addiction and chronic stress |
| title_full |
Dyshomeostasis, obesity, addiction and chronic stress |
| title_fullStr |
Dyshomeostasis, obesity, addiction and chronic stress |
| title_full_unstemmed |
Dyshomeostasis, obesity, addiction and chronic stress |
| title_sort |
dyshomeostasis, obesity, addiction and chronic stress |
| description |
When eating control is overridden by hedonic reward, a condition of obesity dyshomeostasis occurs. Appetitive hedonic reward is a natural response to an obesogenic environment containing endemic stress and easily accessible and palatable high-energy foods and beverages. Obesity dyshomeostasis is mediated by the prefrontal cortex, amygdala and hypothalamic–pituitary–adrenal axis. The ghrelin axis provides the perfect signalling system for feeding dyshomeostasis, affect control and hedonic reward. Dyshomeostasis plays a central role in obesity causation, the addictions and chronic conditions and in persons with diverse bodies. Prevention and treatment efforts that target sources of dyshomeostasis provide ways of reducing adiposity, ameliorating the health impacts of addiction and raising the quality of life in people suffering from chronic stress. |
| publisher |
SAGE Publications |
| publishDate |
2016 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193275/ |
| _version_ |
1613835079969144832 |