Molecular driver alterations and their clinical relevance in cancer of unknown primary site

Cancer of unknown primary (CUP) is defined as metastatic solid malignancy where no primary tumor is detected despite appropriate staging. About 90% of CUP represent adenocarcinoma or undifferentiated carcinoma. Since therapy regimens are only modestly effective, identification of the molecular lands...

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Bibliographic Details
Main Authors: Löffler, Harald, Pfarr, Nicole, Kriegsmann, Mark, Endris, Volker, Hielscher, Thomas, Lohneis, Philipp, Folprecht, Gunnar, Stenzinger, Albrecht, Dietel, Manfred, Weichert, Wilko, Krämer, Alwin
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190099/