miR-22 inhibits tumor growth and metastasis by targeting ATP citrate lyase: evidence in osteosarcoma, prostate cancer, cervical cancer and lung cancer

miR-22 inhibits tumor growth and metastasis by targeting ATP citrate lyase: evidence in osteosarcoma, prostate cancer, cervical cancer and lung cancer

MicroRNAs (miRNAs) are non-coding small RNAs that function as negative regulators of gene expression involving in the tumor biology. ATP citrate lyase (ACLY), a key enzyme initiating de novo lipid synthesis, has been found to be upregulated in cancer cells, and its inhibition causes suppressive effe...

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Bibliographic Details
Main Authors: Xin, Mei, Qiao, Zhiguang, Li, Jing, Liu, Jianjun, Song, Shaoli, Zhao, Xiaoping, Miao, Ping, Tang, Tingting, Wang, Lei, Liu, Weichun, Yang, Xiaodi, Dai, Kerong, Huang, Gang
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190093/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190093/

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