Crucial factors of the inflammatory microenvironment (IL-1β/TNF-α/TIMP-1) promote the maintenance of the malignant hemopoietic clone of myelofibrosis: an in vitro study

Crucial factors of the inflammatory microenvironment (IL-1β/TNF-α/TIMP-1) promote the maintenance of the malignant hemopoietic clone of myelofibrosis: an in vitro study

Along with molecular abnormalities (mutations in JAK2, Calreticulin (CALR) and MPL genes), chronic inflammation is the major hallmark of Myelofibrosis (MF). Here, we investigated the in vitro effects of crucial factors of the inflammatory microenvironment (Interleukin (IL)-1β, Tumor Necrosis Factor...

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Bibliographic Details
Main Authors: Sollazzo, Daria, Forte, Dorian, Polverelli, Nicola, Romano, Marco, Perricone, Margherita, Rossi, Lara, Ottaviani, Emanuela, Luatti, Simona, Martinelli, Giovanni, Vianelli, Nicola, Cavo, Michele, Palandri, Francesca, Catani, Lucia
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190072/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190072/

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