Expression and functional characterization of CD33 transcript variants in human acute myeloid leukemia

Expression and functional characterization of CD33 transcript variants in human acute myeloid leukemia

With the demonstration of improved survival of some acute myeloid leukemia (AML) patients with the CD33 antibody-drug conjugate, gemtuzumab ozogamicin (GO), CD33 has been validated as a target for antigen-specific immunotherapy. Since previous studies identified a CD33 splice variant missing exon 2...

Full description

Bibliographic Details
Main Authors: Laszlo, George S., Harrington, Kimberly H., Gudgeon, Chelsea J., Beddoe, Mary E., Fitzgibbon, Matthew P., Ries, Rhonda E., Lamba, Jatinder K., McIntosh, Martin W., Meshinchi, Soheil, Walter, Roland B.
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190023/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190023/

Similar Items