Stage-Specific Changes in Plasmodium Metabolism Required for Differentiation and Adaptation to Different Host and Vector Environments

Malaria parasites (Plasmodium spp.) encounter markedly different (nutritional) environments during their complex life cycles in the mosquito and human hosts. Adaptation to these different host niches is associated with a dramatic rewiring of metabolism, from a highly glycolytic metabolism in the ase...

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Bibliographic Details
Main Authors: Srivastava, Anubhav, Philip, Nisha, Hughes, Katie R., Georgiou, Konstantina, MacRae, James I., Barrett, Michael P., Creek, Darren J., McConville, Malcolm J., Waters, Andrew P.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189940/