Segmental Aging Underlies the Development of a Parkinson Phenotype in the AS/AGU Rat
There is a paucity of information on the molecular biology of aging processes in the brain. We have used biomarkers of aging (SA β-Gal, p16Ink4a, Sirt5, Sirt6, and Sirt7) to demonstrate the presence of an accelerated aging phenotype across different brain regions in the AS/AGU rat, a spontaneous Par...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
MDPI
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187522/ |