The Novel Aminomethylcycline Omadacycline Has High Specificity for the Primary Tetracycline-Binding Site on the Bacterial Ribosome

The Novel Aminomethylcycline Omadacycline Has High Specificity for the Primary Tetracycline-Binding Site on the Bacterial Ribosome

Omadacycline is an aminomethylcycline antibiotic with potent activity against many Gram-positive and Gram-negative pathogens, including strains carrying the major efflux and ribosome protection resistance determinants. This makes it a promising candidate for therapy of severe infectious diseases. Om...

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Bibliographic Details
Main Authors: Heidrich, Corina G., Mitova, Sanya, Schedlbauer, Andreas, Connell, Sean R., Fucini, Paola, Steenbergen, Judith N., Berens, Christian
Format: Online
Language:English
Published: MDPI 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187513/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187513/

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