CD4 T Follicular Helper and Regulatory Cell Dynamics and Function in HIV Infection

T follicular helper cells (TFH) are a specialized subset of CD4 T cells that reside in B cell follicles and promote B cell maturation into plasma cells and long-lived memory B cells. During chronic infection prior to the development of AIDS, HIV-1 (HIV) replication is largely concentrated in TFH. Pa...

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Bibliographic Details
Main Authors: Miles, Brodie, Miller, Shannon M., Connick, Elizabeth
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187376/