Embryonic Mutant Huntingtin Aggregate Formation in Mouse Models of Huntington’s Disease
The role of aggregate formation in the pathophysiology of Huntington’s disease (HD) remains uncertain. However, the temporal appearance of aggregates tends to correlate with the onset of symptoms and the numbers of neuropil aggregates correlate with the progression of clinical disease. Using highly...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
IOS Press
2016
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181660/ |