The heritability and patterns of DNA methylation in normal human colorectum

DNA methylation (DNAm) has been linked to changes in chromatin structure, gene expression and disease. The DNAm level can be affected by genetic variation; although, how this differs by CpG dinucleotide density and genic location of the DNAm site is not well understood. Moreover, the effect of disea...

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Bibliographic Details
Main Authors: Rowlatt, Amy, Hernández-Suárez, Gustavo, Sanabria-Salas, María Carolina, Serrano-López, Martha, Rawlik, Konrad, Hernandez-Illan, Eva, Alenda, Cristina, Castillejo, Adela, Soto, Jose Luis, Haley, Chris S., Tenesa, Albert
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181623/