Selection and Characterization of Tau Binding ᴅ-Enantiomeric Peptides with Potential for Therapy of Alzheimer Disease

A variety of neurodegenerative disorders, including Alzheimer disease (AD), are associated with neurofibrillary tangles composed of the tau protein, as well as toxic tau oligomers. Inhibitors of pathological tau aggregation, interrupting tau self-assembly, might be useful for the development of ther...

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Bibliographic Details
Main Authors: Dammers, Christina, Yolcu, Deniz, Kukuk, Laura, Willbold, Dieter, Pickhardt, Marcus, Mandelkow, Eckhard, Horn, Anselm H. C., Sticht, Heinrich, Malhis, Marwa Nidal, Will, Nadja, Schuster, Judith, Funke, Susanne Aileen
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179029/