A20 Curtails Primary but Augments Secondary CD8+ T Cell Responses in Intracellular Bacterial Infection

A20 Curtails Primary but Augments Secondary CD8+ T Cell Responses in Intracellular Bacterial Infection

The ubiquitin-modifying enzyme A20, an important negative feedback regulator of NF-κB, impairs the expansion of tumor-specific CD8+ T cells but augments the proliferation of autoimmune CD4+ T cells. To study the T cell-specific function of A20 in bacterial infection, we infected T cell-specific A20...

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Bibliographic Details
Main Authors: Just, Sissy, Nishanth, Gopala, Buchbinder, Jörn H., Wang, Xu, Naumann, Michael, Lavrik, Inna, Schlüter, Dirk
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177869/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177869/

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