Exploiting the Achilles’ heel of membrane trafficking in trypanosomes

•Development of new drugs against trypanosomes is a crucial but unmet need.•Membrane transport, endocytosis and related processes have been proposed as drug targets.•Recent insights uncovered the mode of action of two drugs that are already in the clinic.•Both of these drugs, suramin and pentamidine...

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Bibliographic Details
Main Authors: Zoltner, Martin, Horn, David, de Koning, Harry P, Field, Mark C
Format: Online
Language:English
Published: Current Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176092/