MRI FLAIR lesion segmentation in multiple sclerosis: Does automated segmentation hold up with manual annotation?

•Fully automated and manual MS lesion segmentation on FLAIR images were compared.•Automated FLAIR lesion volume segmentation holds up with manual annotation.•When using DC and ICC, SPM8 based algorithm performed better than recent updates.

Bibliographic Details
Main Authors: Egger, Christine, Opfer, Roland, Wang, Chenyu, Kepp, Timo, Sormani, Maria Pia, Spies, Lothar, Barnett, Michael, Schippling, Sven
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175993/