Function-driven discovery of disease genes in zebrafish using an integrated genomics big data resource

Whole exome sequencing (WES) accelerates disease gene discovery using rare genetic variants, but further statistical and functional evidence is required to avoid false-discovery. To complement variant-driven disease gene discovery, here we present function-driven disease gene discovery in zebrafish...

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Bibliographic Details
Main Authors: Shim, Hongseok, Kim, Ji Hyun, Kim, Chan Yeong, Hwang, Sohyun, Kim, Hyojin, Yang, Sunmo, Lee, Ji Eun, Lee, Insuk
Format: Online
Language:English
Published: Oxford University Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175370/