Estrogen receptor beta reduces colon cancer metastasis through a novel miR-205 - PROX1 mechanism

Estrogen receptor beta reduces colon cancer metastasis through a novel miR-205 - PROX1 mechanism

Colon cancer is a common cause of cancer death in the Western world. Accumulating evidence supports a protective role of estrogen via estrogen receptor beta (ERβ) but the mechanism of action is not known. Here, we elucidate a molecular mechanism whereby ERβ represses the oncogenic prospero homebox 1...

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Bibliographic Details
Main Authors: Nguyen-Vu, Trang, Wang, Jun, Mesmar, Fahmi, Mukhopadhyay, Srijita, Saxena, Ashish, McCollum, Catherine W., Gustafsson, Jan-Åke, Bondesson, Maria, Williams, Cecilia
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173124/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173124/

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