Characterization and use of HapT1-derived homologous tumors as a preclinical model to evaluate therapeutic efficacy of drugs against pancreatic tumor desmoplasia

Characterization and use of HapT1-derived homologous tumors as a preclinical model to evaluate therapeutic efficacy of drugs against pancreatic tumor desmoplasia

Desmoplasia in human pancreatic cancer (PC) promotes cancer progression and hinders effective drug delivery. The objectives of this study were to characterize a homologous orthotopic model of PC in Syrian golden hamster and investigate the effect of anti-fibrotic (pirfenidone), antioxidant (N-acetyl...

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Bibliographic Details
Main Authors: Suklabaidya, Sujit, Das, Biswajit, Ali, Syed Azmal, Jain, Sumeet, Swaminathan, Sharada, Mohanty, Ashok K., Panda, Susen K., Dash, Pujarini, Chakraborty, Subhankar, Batra, Surinder K., Senapati, Shantibhusan
Format: Online
Language:English
Published: Impact Journals LLC 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173099/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5173099/

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