Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study

James Brenton and colleagues reveal tumour burden and prognosis correlations from circulating DNA analysis in high grade serous ovarian carcinoma.

Bibliographic Details
Main Authors: Parkinson, Christine A., Gale, Davina, Piskorz, Anna M., Biggs, Heather, Hodgkin, Charlotte, Addley, Helen, Freeman, Sue, Moyle, Penelope, Sala, Evis, Sayal, Karen, Hosking, Karen, Gounaris, Ioannis, Jimenez-Linan, Mercedes, Earl, Helena M., Qian, Wendi, Rosenfeld, Nitzan, Brenton, James D.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172526/
id pubmed-5172526
recordtype oai_dc
spelling pubmed-51725262017-01-04 Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study Parkinson, Christine A. Gale, Davina Piskorz, Anna M. Biggs, Heather Hodgkin, Charlotte Addley, Helen Freeman, Sue Moyle, Penelope Sala, Evis Sayal, Karen Hosking, Karen Gounaris, Ioannis Jimenez-Linan, Mercedes Earl, Helena M. Qian, Wendi Rosenfeld, Nitzan Brenton, James D. Research Article James Brenton and colleagues reveal tumour burden and prognosis correlations from circulating DNA analysis in high grade serous ovarian carcinoma. Public Library of Science 2016-12-20 /pmc/articles/PMC5172526/ /pubmed/27997533 http://dx.doi.org/10.1371/journal.pmed.1002198 Text en © 2016 Parkinson et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Parkinson, Christine A.
Gale, Davina
Piskorz, Anna M.
Biggs, Heather
Hodgkin, Charlotte
Addley, Helen
Freeman, Sue
Moyle, Penelope
Sala, Evis
Sayal, Karen
Hosking, Karen
Gounaris, Ioannis
Jimenez-Linan, Mercedes
Earl, Helena M.
Qian, Wendi
Rosenfeld, Nitzan
Brenton, James D.
spellingShingle Parkinson, Christine A.
Gale, Davina
Piskorz, Anna M.
Biggs, Heather
Hodgkin, Charlotte
Addley, Helen
Freeman, Sue
Moyle, Penelope
Sala, Evis
Sayal, Karen
Hosking, Karen
Gounaris, Ioannis
Jimenez-Linan, Mercedes
Earl, Helena M.
Qian, Wendi
Rosenfeld, Nitzan
Brenton, James D.
Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study
author_facet Parkinson, Christine A.
Gale, Davina
Piskorz, Anna M.
Biggs, Heather
Hodgkin, Charlotte
Addley, Helen
Freeman, Sue
Moyle, Penelope
Sala, Evis
Sayal, Karen
Hosking, Karen
Gounaris, Ioannis
Jimenez-Linan, Mercedes
Earl, Helena M.
Qian, Wendi
Rosenfeld, Nitzan
Brenton, James D.
author_sort Parkinson, Christine A.
title Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study
title_short Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study
title_full Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study
title_fullStr Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study
title_full_unstemmed Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study
title_sort exploratory analysis of tp53 mutations in circulating tumour dna as biomarkers of treatment response for patients with relapsed high-grade serous ovarian carcinoma: a retrospective study
description James Brenton and colleagues reveal tumour burden and prognosis correlations from circulating DNA analysis in high grade serous ovarian carcinoma.
publisher Public Library of Science
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172526/
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