Counteracting bone fragility with human amniotic mesenchymal stem cells

The impaired maturation of bone-forming osteoblasts results in reduced bone formation and subsequent bone weakening, which leads to a number of conditions such as osteogenesis imperfecta (OI). Transplantation of human fetal mesenchymal stem cells has been proposed as skeletal anabolic therapy to enh...

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Bibliographic Details
Main Authors: Ranzoni, Anna M., Corcelli, Michelangelo, Hau, Kwan-Leong, Kerns, Jemma G., Vanleene, Maximilien, Shefelbine, Sandra, Jones, Gemma N., Moschidou, Dafni, Dala-Ali, Benan, Goodship, Allen E., De Coppi, Paolo, Arnett, Timothy R., Guillot, Pascale V.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171815/